Clinical evaluation of microbicide formulations
نویسندگان
چکیده
منابع مشابه
Microbicide clinical trial adherence: insights for introduction
After two decades of microbicide clinical trials it remains uncertain if vaginally- delivered products will be clearly shown to reduce the risk of HIV infection in women and girls. Furthermore, a microbicide product with demonstrated clinical efficacy must be used correctly and consistently if it is to prevent infection. Information on adherence that can be gleaned from microbicide trials is re...
متن کاملDevelopment of an Analytical Method for the Rapid Quantitation of Peptides Used in Microbicide Formulations
Recently, a growing number of macromolecules such as peptides and proteins have been formulated into various microbicide formulations for the prevention of sexually transmitted infections. However, a fast and reliable high-throughput method for quantitating peptide/protein in polymer-based microbicide formulations is still lacking. As a result, we developed and validated a reversed-phase high-p...
متن کاملSusceptibility of Chlamydia trachomatis to excipients commonly used in topical microbicide formulations.
Commonly used "inactive" pharmaceutical excipients were tested in a previously developed minimum cidal concentration assay to assess their ability to kill Chlamydia trachomatis topically. Sixteen excipients were evaluated in these studies under various conditions. A range of activities was found among the excipients that could be tested in our assay system.
متن کاملEvaluation of aquarium antibiotic formulations.
The antibacterial activity of eight products marketed for the therapy and prophylaxis of diseases of ornamental fishes was tested. The products contained erythromycin, neomycin, a nitrofuran, penicillin, sulfa compounds, streptomycin, or tetracycline. When used at the concentration recommended by the manufacturer, the products failed to inhibit the growth of bacterial species known to be potent...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Antiviral Research
سال: 2010
ISSN: 0166-3542
DOI: 10.1016/j.antiviral.2010.09.008